
Sorenson fastest in Happy Hour: #32-Reed Sorenson was quickest during the final practice session at Nashville with a speed of 158.157mph. He was followed by: #99-Trevor Bayne, #22-Brad Keselowski, #60-Carl Edwards, #18-Kyle Busch, #66-Steve Wallace, #33-Kevin Harvick, #38-Jason Leffler, #20-Joey Logano, and #15-Michael Annett. #2-Tim Schendel spun. No other accidents were reported.(4-2-2010)
| Pos | Car | Driver | Team | Time | Speed | # Laps |
| 1 | 32 | Reed Sorenson | Dollar General Toyota | 30.342 | 158.157 | 30 |
| 2 | 99 | Trevor Bayne | Diamond-Waltrip Racing Toyota | 30.349 | 158.121 | 24 |
| 3 | 22 | Brad Keselowski | Discount Tire Dodge | 30.368 | 158.022 | 27 |
| 4 | 60 | Carl Edwards | Valvoline Ford | 30.414 | 157.783 | 27 |
| 5 | 18 | Kyle Busch | Z-Line Designs Toyota | 30.417 | 157.767 | 37 |
| 6 | 66 | Steve Wallace | 5-hour Energy Toyota | 30.448 | 157.606 | 22 |
| 7 | 33 | Kevin Harvick | Armour Chevy | 30.472 | 157.482 | 27 |
| 8 | 38 | Jason Leffler | Great Clips Toyota | 30.480 | 157.441 | 14 |
| 9 | 20 | Joey Logano | GameStop/Legend of Zork Toyota | 30.485 | 157.415 | 36 |
| 10 | 15 | Michael Annett | Pilot Travel Centers Toyota | 30.492 | 157.379 | 28 |
| 11 | 88 | Kelly Bires | Suave Men Chevy | 30.494 | 157.369 | 38 |
| 12 | 21 | John Wes Townley | Zaxby's Chevy | 30.494 | 157.369 | 30 |
| 13 | 12 | Justin Allgaier | Verizon Wireless Dodge | 30.553 | 157.065 | 40 |
| 14 | 1 | James Buescher # | Phoenix Racing Chevy | 30.580 | 156.926 | 40 |
| 15 | 10 | Mikey Kile | Accudoc Toyota | 30.590 | 156.875 | 30 |
| 16 | 7 | Scott Wimmer | Lifetime Army Wives Chevy | 30.624 | 156.701 | 24 |
| 17 | 43 | Scott Lagasse Jr. | Broken Bow Records/Jason Aldean Ford | 30.626 | 156.690 | 29 |
| 18 | 11 | Brian Scott # | Dollar General Toyota | 30.642 | 156.609 | 26 |
| 19 | 16 | Colin Braun # | Con-way Ford | 30.702 | 156.303 | 28 |
| 20 | 70 | Shelby Howard | ForeTravel Chevy | 30.728 | 156.170 | 24 |
| 21 | 81 | Michael McDowell | MOBILE-Shop.com Dodge | 30.746 | 156.079 | 19 |
| 22 | 35 | Jason Keller | Tri-Star Motorsports Chevy | 30.758 | 156.018 | 20 |
| 23 | 27 | Johnny Sauter | Red Man Moist Snuff Ford | 30.783 | 155.891 | 18 |
| 24 | 90 | Danny O'Quinn Jr. | D'Hondt Humphrey Motorsports Chevy | 30.785 | 155.881 | 2 |
| 25 | 91 | Chase Miller | D'Hondt Humphrey Motorsports Chevy | 30.787 | 155.871 | 2 |
| 26 | 62 | Brendan Gaughan | South Point Hotel & Casino Toyota | 30.789 | 155.861 | 22 |
| 27 | 87 | Joe Nemechek | FrontRowJoe.com Chevy | 30.795 | 155.830 | 25 |
| 28 | 89 | Morgan Shepherd | Faith Motorsports Chevy | 30.800 | 155.805 | 5 |
| 29 | 98 | Paul Menard | Richmond/Menards Ford | 30.809 | 155.760 | 27 |
| 30 | 09 | Scott Riggs | Ford Drive one. Ford | 30.809 | 155.760 | 26 |
| 31 | 56 | Kevin Lepage | MacHill Motorsports Chevy | 30.809 | 155.760 | 9 |
| 32 | 34 | Tony Raines | Long John Silver's Chevy | 30.851 | 155.548 | 16 |
| 33 | 6 | Ricky Stenhouse Jr. # | CitiFinancial Ford | 30.864 | 155.482 | 28 |
| 34 | 73 | Derrike Cope | Charter Dodge | 30.997 | 154.815 | 9 |
| 35 | 02 | Andy Ponstein | CorrieStottRacing.com Chevy | 31.024 | 154.680 | 14 |
| 36 | 40 | Mike Bliss | Key Motorsports Chevy | 31.033 | 154.635 | 25 |
| 37 | 05 | Willie Allen | FoxRidge Homes/31-W Insulation | 31.051 | 154.546 | 13 |
| 38 | 04 | Jeremy Clements | Boudreaux's Butt Paste Chevy | 31.065 | 154.476 | 11 |
| 39 | 28 | Kenny Wallace | Bear Hunting Magazine/Federated Chevy | 31.096 | 154.322 | 11 |
| 40 | 92 | Dennis Setzer | K-Automotive Motorsports Dodge | 31.099 | 154.307 | 10 |
| 41 | 61 | Josh Wise | Courtyard Marriott Ford | 31.109 | 154.258 | 18 |
| 42 | 01 | Mike Wallace | Monster Diesel Chevy | 31.186 | 153.877 | 11 |
| 43 | 26 | Brian Keselowski | K-Automotive Motorsports Dodge | 31.250 | 153.562 | 24 |
| 44 | 23 | Robert Richardson Jr. | R3 Motorsports Chevy | 31.427 | 152.697 | 23 |
| 45 | 24 | Eric McClure | Hefty Ford | 31.623 | 151.750 | 36 |
| 46 | 75 | Brett Rowe | DuVita Chevy | 40.437 | 118.673 | 2 |
| 47 | 52 | Tim Schendel | Jimmy Means Racing Chevy | 0.000 | 0.000 | 0 |
Edwards fastest in opening practice: #60-Carl Edward was the fastest in the opening practice session for the Nashville 300. His top speed was 157.209mph. #22-Brad Keselowski was second followed by #12-Justin Allgaier, #38-Jason Leffler, #32-Reed Sorenson, #33-Kevin Harvick, #18-Kyle Busch, #20-Joey Logano, #66-Steve Wallace, and #27-Johnny Sauter. #11-Brian Scott spun during the session but did not hit anything. #23-Robert Richardson wrecked and will have to go to a backup.(4-2-2010)
| Pos | Car | Driver | Team | Time | Speed | # Laps |
| 1 | 60 | Carl Edwards | Valvoline Ford | 30.525 | 157.209 | 21 |
| 2 | 22 | Brad Keselowski | Discount Tire Dodge | 30.577 | 156.941 | 25 |
| 3 | 12 | Justin Allgaier | Verizon Wireless Dodge | 30.632 | 156.660 | 28 |
| 4 | 38 | Jason Leffler | Great Clips Toyota | 30.673 | 156.450 | 41 |
| 5 | 32 | Reed Sorenson | Dollar General Toyota | 30.696 | 156.333 | 34 |
| 6 | 33 | Kevin Harvick | Armour Chevy | 30.716 | 156.231 | 17 |
| 7 | 18 | Kyle Busch | Z-Line Designs Toyota | 30.730 | 156.160 | 20 |
| 8 | 20 | Joey Logano | GameStop/Legend of Zork Toyota | 30.771 | 155.952 | 34 |
| 9 | 66 | Steve Wallace | 5-hour Energy Toyota | 30.844 | 155.583 | 22 |
| 10 | 27 | Johnny Sauter | Red Man Moist Snuff Ford | 30.909 | 155.256 | 31 |
| 11 | 88 | Kelly Bires | Suave Men Chevy | 30.921 | 155.195 | 28 |
| 12 | 98 | Paul Menard | Richmond/Menards Ford | 30.939 | 155.105 | 27 |
| 13 | 16 | Colin Braun # | Con-way Ford | 30.945 | 155.075 | 39 |
| 14 | 91 | Chase Miller | D'Hondt Humphrey Motorsports Chevy | 30.978 | 154.910 | 9 |
| 15 | 11 | Brian Scott # | Dollar General Toyota | 30.982 | 154.890 | 19 |
| 16 | 09 | Scott Riggs | Ford Drive one. Ford | 30.994 | 154.830 | 23 |
| 17 | 15 | Michael Annett | Pilot Travel Centers Toyota | 31.022 | 154.690 | 31 |
| 18 | 21 | John Wes Townley | Zaxby's Chevy | 31.023 | 154.685 | 30 |
| 19 | 70 | Shelby Howard | ForeTravel Chevy | 31.027 | 154.665 | 30 |
| 20 | 62 | Brendan Gaughan | South Point Hotel & Casino Toyota | 31.033 | 154.635 | 26 |
| 21 | 1 | James Buescher # | Phoenix Racing Chevy | 31.041 | 154.596 | 41 |
| 22 | 99 | Trevor Bayne | Diamond-Waltrip Racing Toyota | 31.064 | 154.481 | 20 |
| 23 | 6 | Ricky Stenhouse Jr. # | CitiFinancial Ford | 31.068 | 154.461 | 36 |
| 24 | 90 | Danny O'Quinn Jr. | D'Hondt Humphrey Motorsports Chevy | 31.074 | 154.431 | 4 |
| 25 | 49 | Mark Green | Jay Robinson Racing Chevy | 31.116 | 154.223 | 5 |
| 26 | 35 | Jason Keller | Tri-Star Motorsports Chevy | 31.121 | 154.198 | 37 |
| 27 | 87 | Joe Nemechek | FrontRowJoe.com Chevy | 31.136 | 154.124 | 16 |
| 28 | 81 | Michael McDowell | MOBILE-Shop.com Dodge | 31.147 | 154.069 | 20 |
| 29 | 73 | Derrike Cope | Charter Dodge | 31.169 | 153.961 | 13 |
| 30 | 10 | Mikey Kile | Accudoc Toyota | 31.203 | 153.793 | 33 |
| 31 | 89 | Morgan Shepherd | Faith Motorsports Chevy | 31.209 | 153.763 | 10 |
| 32 | 34 | Tony Raines | Long John Silver's Chevy | 31.228 | 153.670 | 17 |
| 33 | 26 | Brian Keselowski | K-Automotive Motorsports Dodge | 31.287 | 153.380 | 30 |
| 34 | 7 | Scott Wimmer | Lifetime Army Wives Chevy | 31.290 | 153.365 | 19 |
| 35 | 05 | Willie Allen | FoxRidge Homes/31-W Insulation | 31.361 | 153.018 | 21 |
| 36 | 56 | Kevin Lepage | MacHill Motorsports Chevy | 31.373 | 152.960 | 5 |
| 37 | 01 | Mike Wallace | Monster Diesel Chevy | 31.400 | 152.828 | 28 |
| 38 | 43 | Scott Lagasse Jr. | Broken Bow Records/Jason Aldean Ford | 31.438 | 152.643 | 24 |
| 39 | 04 | Jeremy Clements | Boudreaux's Butt Paste Chevy | 31.460 | 152.537 | 24 |
| 40 | 61 | Josh Wise | Courtyard Marriott Ford | 31.481 | 152.435 | 21 |
| 41 | 92 | Dennis Setzer | K-Automotive Motorsports Dodge | 31.500 | 152.343 | 9 |
| 42 | 52 | Tim Schendel | Jimmy Means Racing Chevy | 31.594 | 151.890 | 15 |
| 43 | 28 | Kenny Wallace | Bear Hunting Magazine/Federated Chevy | 31.653 | 151.606 | 3 |
| 44 | 02 | Andy Ponstein | CorrieStottRacing.com Chevy | 31.674 | 151.506 | 14 |
| 45 | 40 | Mike Bliss | Key Motorsports Chevy | 31.762 | 151.086 | 8 |
| 46 | 24 | Eric McClure | Hefty Ford | 32.051 | 149.724 | 21 |
| 47 | 23 | Robert Richardson Jr. | R3 Motorsports Chevy | 32.598 | 147.211 | 6 |
