
Harvick fastest in Happy Hour: #33-Kevin Harvick was quickest during the final practice session at Talladega with a speed of 193.929mph. He was followed by:#18-Kyle Busch, #22-Brad Keselowski, #21-Clint Bowyer, #12-Justin Allgaier, #34-Tony Raines, #99-Trevor Bayne, #6-Ricky Stenhouse, #23-Robert Richardson, and #66-Steve Wallace. There were no accidents reported.(4-22-2010)
| Pos | Car | Driver | Team | Time | Speed | # Laps |
| 1 | 33 | Kevin Harvick | Rheem Chevy | 49.379 | 193.929 | 12 |
| 2 | 18 | Kyle Busch | Z-Line Designs Toyota | 49.385 | 193.905 | 14 |
| 3 | 22 | Brad Keselowski | Discount Tire Dodge | 49.635 | 192.928 | 17 |
| 4 | 21 | Clint Bowyer | Zaxby's Chevy | 49.640 | 192.909 | 13 |
| 5 | 12 | Justin Allgaier | Verizon Wireless Dodge | 49.656 | 192.847 | 18 |
| 6 | 34 | Tony Raines | Long John Silver's Chevy | 49.710 | 192.637 | 27 |
| 7 | 99 | Trevor Bayne | Aaron's Dream Machine Toyota | 49.796 | 192.305 | 15 |
| 8 | 6 | Ricky Stenhouse Jr. # | CitiFinancial Ford | 49.805 | 192.270 | 22 |
| 9 | 23 | Robert Richardson Jr. | R3 Motorsports Chevy | 49.834 | 192.158 | 18 |
| 10 | 66 | Steve Wallace | 5-Hour Energy Toyota | 49.882 | 191.973 | 16 |
| 11 | 27 | Scott Wimmer | Redman Moist Snuff Ford | 49.906 | 191.881 | 20 |
| 12 | 24 | Eric McClure | Hefty Ford | 49.908 | 191.873 | 13 |
| 13 | 38 | Jason Leffler | Great Clips Toyota | 49.978 | 191.604 | 19 |
| 14 | 62 | Brendan Gaughan | South Point Casino & Hotel Toyota | 49.996 | 191.535 | 12 |
| 15 | 20 | Joey Logano | GameStop Toyota | 49.998 | 191.528 | 12 |
| 16 | 88 | Jamie McMurray | Hellmann's Chevy | 50.016 | 191.459 | 20 |
| 17 | 7 | Steve Arpin | JR Motorsports Chevy | 50.155 | 190.928 | 21 |
| 18 | 1 | James Buescher # | Phoenix Racing Chevy | 50.259 | 190.533 | 11 |
| 19 | 09 | Patrick Sheltra | RAB Racing Ford | 50.318 | 190.310 | 31 |
| 20 | 01 | Mike Wallace | Choctaw Casino - Resort Chevy | 50.375 | 190.094 | 17 |
| 21 | 87 | Joe Nemechek | NEMCO Motorsports Chevy | 50.417 | 189.936 | 13 |
| 22 | 43 | Scott Lagasse Jr. | Autism Awareness / O'Reilly Auto Parts Ford | 50.627 | 189.148 | 13 |
| 23 | 81 | Michael McDowell | MOBILE-Shop Dodge | 50.662 | 189.017 | 16 |
| 24 | 04 | Jeremy Clements | Boudreaux's Butt Paste Chevy | 50.670 | 188.988 | 6 |
| 25 | 70 | Shelby Howard | ForeTravel Motorcoach Chevy | 50.727 | 188.775 | 9 |
| 26 | 11 | Brian Scott # | AccuDoc Solutions Toyota | 51.772 | 184.965 | 8 |
| 27 | 42 | Parker Kligerman # | Smith Ironmworks Dodge | 51.826 | 184.772 | 11 |
| 28 | 35 | Jason Keller | TriStar Motorsports Chevy | 51.848 | 184.694 | 11 |
| 29 | 0 | Chrissy Wallace | JDavisMotorsports.com Chevy | 51.882 | 184.573 | 11 |
| 30 | 16 | Colin Braun # | Con-way Freight Ford | 51.918 | 184.445 | 11 |
| 31 | 98 | Paul Menard | Tide / Menards Ford | 52.087 | 183.846 | 6 |
| 32 | 73 | Derrike Cope | Charter Dodge | 52.252 | 183.266 | 11 |
| 33 | 52 | Donnie Neuenberger | I-Hop Chevy | 52.319 | 183.031 | 7 |
| 34 | 92 | Dennis Setzer | K-Automotive Motorsports Dodge | 52.339 | 182.961 | 3 |
| 35 | 15 | Michael Annett | Pilot Travel Centers Toyota | 52.437 | 182.619 | 3 |
| 36 | 10 | Reed Sorenson | Braun Racing Toyota | 52.492 | 182.428 | 3 |
| 37 | 89 | Morgan Shepherd | DealTaker.com Chevy | 52.525 | 182.313 | 8 |
| 38 | 26 | Brian Keselowski | Stubb's BBQ Dodge | 52.525 | 182.313 | 3 |
| 39 | 56 | Kevin Lepage | Mac Hill Motorsports Toyota | 52.560 | 182.192 | 10 |
| 40 | 49 | Mark Green | Jay Robinson Inc. Chevy | 52.565 | 182.174 | 7 |
| 41 | 83 | John Borneman III | Red Line Oil Dodge | 52.820 | 181.295 | 7 |
| 42 | 05 | Willie Allen | 31W Insulation Chevy | 53.021 | 180.608 | 11 |
| 43 | 61 | Josh Wise | Specialty Racing Ford | 53.068 | 180.448 | 6 |
| 44 | 75 | Bobby Gerhart | Lucas Oil Chevy | 54.946 | 174.280 | 2 |
Annett fastest in opening practice: #15-Michael Annett was the fastest in the opening practice session for the Aaron's 312. His top speed was 193.466mph. #34-Tony Raines was second. The rest of the top 10: #12-Justin Allgaier, #22-Brad Keselowski, #21-Clint Bowyer, #33-Kevin Harvick, #20-Joey Logano, #99-Trevor Bayne, #18-Kyle Busch, and #62-Brendan Gaughan. There were no accidents reported.(4-22-2010)
| Pos | Car | Driver | Team | Time | Speed | # Laps |
| 1 | 15 | Michael Annett | Pilot Travel Centers Toyota | 49.497 | 193.466 | 14 |
| 2 | 34 | Tony Raines | Long John Silver's Chevy | 49.508 | 193.423 | 11 |
| 3 | 12 | Justin Allgaier | Verizon Wireless Dodge | 49.693 | 192.703 | 18 |
| 4 | 22 | Brad Keselowski | Discount Tire Dodge | 49.810 | 192.251 | 12 |
| 5 | 21 | Clint Bowyer | Zaxby's Chevy | 49.921 | 191.823 | 16 |
| 6 | 33 | Kevin Harvick | Rheem Chevy | 49.923 | 191.815 | 11 |
| 7 | 20 | Joey Logano | GameStop Toyota | 49.933 | 191.777 | 11 |
| 8 | 99 | Trevor Bayne | Aaron's Dream Machine Toyota | 49.969 | 191.639 | 21 |
| 9 | 18 | Kyle Busch | Z-Line Designs Toyota | 49.988 | 191.566 | 15 |
| 10 | 62 | Brendan Gaughan | South Point Casino & Hotel Toyota | 50.019 | 191.447 | 6 |
| 11 | 11 | Brian Scott # | AccuDoc Solutions Toyota | 50.048 | 191.336 | 14 |
| 12 | 60 | Carl Edwards | Fastenal Ford | 50.110 | 191.100 | 12 |
| 13 | 10 | Reed Sorenson | Braun Racing Toyota | 50.132 | 191.016 | 7 |
| 14 | 88 | Jamie McMurray | Hellmann's Chevy | 50.207 | 190.730 | 11 |
| 15 | 43 | Scott Lagasse Jr. | Autism Awareness / O'Reilly Auto Parts Ford | 50.233 | 190.632 | 17 |
| 16 | 32 | Brian Vickers | Dollar General Toyota | 50.281 | 190.450 | 10 |
| 17 | 98 | Paul Menard | Tide / Menards Ford | 50.299 | 190.382 | 15 |
| 18 | 1 | James Buescher # | Phoenix Racing Chevy | 50.303 | 190.366 | 13 |
| 19 | 7 | Steve Arpin | JR Motorsports Chevy | 50.424 | 189.910 | 20 |
| 20 | 27 | Scott Wimmer | Redman Moist Snuff Ford | 50.628 | 189.144 | 11 |
| 21 | 38 | Jason Leffler | Great Clips Toyota | 50.631 | 189.133 | 10 |
| 22 | 28 | Kenny Wallace | Anderson's Maple Syrup Chevy | 50.814 | 188.452 | 7 |
| 23 | 23 | Robert Richardson Jr. | R3 Motorsports Chevy | 51.076 | 187.485 | 10 |
| 24 | 42 | Parker Kligerman # | Smith Ironmworks Dodge | 52.028 | 184.055 | 7 |
| 25 | 70 | Shelby Howard | ForeTravel Motorcoach Chevy | 52.036 | 184.026 | 7 |
| 26 | 6 | Ricky Stenhouse Jr. # | CitiFinancial Ford | 52.070 | 183.906 | 11 |
| 27 | 16 | Colin Braun # | Con-way Freight Ford | 52.166 | 183.568 | 10 |
| 28 | 35 | Jason Keller | TriStar Motorsports Chevy | 52.310 | 183.063 | 7 |
| 29 | 09 | Patrick Sheltra | RAB Racing Ford | 52.348 | 182.930 | 9 |
| 30 | 26 | Brian Keselowski | Stubb's BBQ Dodge | 52.388 | 182.790 | 3 |
| 31 | 87 | Joe Nemechek | NEMCO Motorsports Chevy | 52.487 | 182.445 | 3 |
| 32 | 04 | Jeremy Clements | Boudreaux's Butt Paste Chevy | 52.507 | 182.376 | 3 |
| 33 | 73 | Derrike Cope | Charter Dodge | 52.616 | 181.998 | 10 |
| 34 | 01 | Mike Wallace | Choctaw Casino - Resort Chevy | 52.689 | 181.746 | 3 |
| 35 | 56 | Kevin Lepage | Mac Hill Motorsports Toyota | 52.691 | 181.739 | 3 |
| 36 | 92 | Dennis Setzer | K-Automotive Motorsports Dodge | 52.810 | 181.329 | 2 |
| 37 | 05 | Willie Allen | 31W Insulation Chevy | 52.862 | 181.151 | 7 |
| 38 | 66 | Steve Wallace | 5-Hour Energy Toyota | 52.888 | 181.062 | 3 |
| 39 | 0 | Chrissy Wallace | JDavisMotorsports.com Chevy | 53.211 | 179.963 | 2 |
| 40 | 40 | Jeff Green | BadBoyBuggies/WldgameInnovation Chev | 66.845 | 143.257 | 1 |
